Telostatin

Telostatin™ is the product of a deliberate investigation into the chemical signals that control the hair growth cycle. The application of a specific bioactive polypeptide - Target Activator 5 (TA₅), to the chemistry of these findings has created a new hair restoration technology for men and women.

Hair grows, rests, and is lost (and starts over) in a regular, normal cyclic pattern that takes several months. Telostatin is the first and only product in its class to DIRECTLY STIMULATE AND PROLONG the anagenic growth phase of the hair cycle using hair-growth promoting factors. This product is also first in its class to DIRECTLY SUPPRESS the catagenic rest and telogenic loss phases of the hair cycle.

During the research, attention was given to other factors that create a hostile environment for hair maintenance and robust growth. Seborrhea and the scalp parasite Demodex are common stressors known to contribute to hair loss. Increasing the blood supply at the hair root has been shown to provide a nutrient-rich environment that favors hair growth. Each of these factors was addressed in the development of Telostatin.

Male volunteers between ages 26 and 50 with moderate degrees of hair loss were enrolled in a 12 week study conducted by independent physicians. Telostatin was applied once daily during the study. Hair cycle analysis was assessed by special photographic enlargements of a representative area of active hair loss and was subjected to computer analysis.

At 8 weeks, 100% of the men treated with Telostatin experienced an increase in hair growth and an average 80% reduction in hair loss. After 12 weeks, hair thickness had increased by 69% while the hair regrowth rate increased 33%. (Regrowth rate combines changes in hair count, hair thickness, and hair growth rate into a single value.)

All study participants with self-described "thin hair" categorized their hair as thicker at the trial's end.

Seborrhea is a disease of the sebacious gland that results in a change in the quality and the amount of the gland's secretions, called sebum. The oily coating, crusts, or scales that develop on the scalp create a hostile environment for hair growth and can be a significant cause of hair loss in many individuals. During the 12 week study, there was a 62% reduction in sebum production for volunteers using Telostatin.

Demodex is a scalp parasite that lives in the sebacious glands. When the Demodex population is high, the parasites' impact on the sebacious gland's ability to function creates an overly dry and hostile environment that favors hair loss. Research proved that colloidal sulphur in Telostatin controlled the Demodex population by reducing it an average of 32%.

**HEAD TO HEAD COMPARISON**
	Telostatin	Propecia (Finasteride)	Rogaine (Minoxidil)
*Directly* stimulates anagenic growth phase with growth factors	YES	NO	NO
*Directly* suppresses catagenic rest and telogenic loss phases	YES	NO	NO
Decreases hair follicle exposure to DHT*	YES	YES	YES
Indirectly suppresses telogenic loss	YES	YES	YES
Increases nutrient bloodflow to hair follicle	YES	NO	NO
Controls seborrhea	YES	NO	NO
Controls Demodex	YES	NO	NO
Use once a day	YES	YES	NO
Safe for men and women	YES	NO	YES
Over-the-counter product	YES	NO	YES**

*DHT (dihydrotestosterone) is the principal cause of male pattern baldness, otherwise known as androgenetic alopecia. Activor's research suggests that DHT at the hair follicle suppresses the release of growth factors necessary for hair growth and maintenance. Continued exposure to DHT in predisposed individuals leads to gradual thinning and loss of hair. Removal of DHT from the hair follicle provides for indirect suppression of the telogenic and, to a lesser extent, the catagenic phases of the hair cycle.

**Propecia is for men only. Pregnant women must not handle tablets or they risk causing a specific birth defect in a male fetus (misdevelopment of the sex organs).

**Rogaine prescription-strength formula is not available over-the-counter.